Marengo CIMS Hospital is dedicated to providing comprehensive healthcare services and fostering patient well-being. As part of our commitment to patient education, we have developed the Marengo CIMS Hospital Medical Encyclopedia—an invaluable online resource designed to empower patients with knowledge about various medical conditions, treatments, and preventive measures. This encyclopedia serves as a trusted and accessible repository of medical information, allowing patients to make informed decisions regarding their health and collaborate more effectively with healthcare professionals.


Ulcerative Colitis (UC) is a chronic inflammatory bowel disease (IBD) that affects millions of people worldwide, including a significant number in India. This article aims to provide a comprehensive understanding of UC, its signs and symptoms, classification, causes, risk factors, diagnostic tests, treatment options, and prevention techniques. All explanations will be presented in layman’s terms to ensure clarity and accessibility for readers.

Signs and Symptoms:

Ulcerative Colitis manifests primarily in the digestive system and is characterized by symptoms such as:

  • Diarrhea: Frequent and urgent bowel movements with loose or bloody stools.
  • Abdominal Pain: Cramping or discomfort in the lower abdomen.
  • Rectal Bleeding: Blood in the stool or on toilet paper.
  • Weight Loss: Unintentional weight loss due to reduced nutrient absorption.
  • Fatigue: Persistent tiredness and lack of energy.
  • Loss of Appetite: Decreased desire to eat.

What Is Ulcerative Colitis? :

Ulcerative Colitis is a chronic inflammatory condition that primarily affects the colon (large intestine) and rectum. It causes inflammation and the formation of ulcers in the lining of the digestive tract, resulting in the aforementioned symptoms.

How Is Ulcerative Colitis Classified? :

There are different classifications of Ulcerative Colitis based on the location and extent of inflammation:

  • Ulcerative Proctitis: Affects only the rectum.
  • Left-Sided Colitis: Inflammation extends from the rectum to the sigmoid and descending colon.
  • Pancolitis: Inflammation affects the entire colon.
  • Fulminant Colitis: Severe and widespread inflammation leading to potentially life-threatening complications.

Causes and Triggers:

The exact cause of Ulcerative Colitis is still unknown, but several factors may contribute to its development, including:

  • Genetics: A family history of UC increases the risk of developing the condition.
  • Immune System Dysfunction: An abnormal immune response may trigger inflammation in the colon.
  • Environmental Factors: Certain environmental factors, such as diet and stress, may influence UC symptoms.
  • Microbiome Imbalance: Alterations in the gut microbiota may play a role in UC.

Risk Factors:

Several factors can increase the risk of developing Ulcerative Colitis, including:

  • Family History: Having a close relative with UC increases the risk.
    • Example: If a parent or sibling has been diagnosed with UC, the chances of developing the condition are higher.
  • Ethnicity: Certain ethnic groups, including people of Indian descent, have a higher susceptibility to UC.
  • Age: Although UC can develop at any age, it most commonly begins during adolescence or early adulthood.
  • Smoking: Smoking tobacco increases the risk of developing UC.

Types of Ulcerative Colitis:

a) Ulcerative Proctitis:

Ulcerative Proctitis affects only the rectum and is the mildest form of UC. It is often associated with symptoms such as rectal bleeding, rectal pain, and a constant feeling of needing to have a bowel movement.

b) Left-Sided Colitis:

Left-Sided Colitis involves inflammation from the rectum to the sigmoid colon and descending colon. Symptoms may include bloody diarrhea, abdominal cramps, and weight loss.

c) Pancolitis:

Pancolitis affects the entire colon and can cause severe symptoms such as severe diarrhea, abdominal pain, fatigue, and weight loss.

Diagnostic Tests:

To diagnose Ulcerative Colitis, several diagnostic tests may be performed, including:

  • Colonoscopy: A procedure in which a flexible tube with a camera is inserted into the colon to examine the lining and collect tissue samples for biopsy.
  • Flexible Sigmoidoscopy: Similar to a colonoscopy, but it only examines the rectum and lower part of the colon.
  • Blood Tests: Blood tests can help determine inflammation levels and rule out other conditions.
  • Stool Sample Analysis: Analyzing stool samples can help identify infections or signs of inflammation in the digestive tract.

Treatment Options:

Treatment for Ulcerative Colitis aims to reduce inflammation, control symptoms, and maintain remission. Some common treatment options include:

  • Medications: Anti-inflammatory drugs, immunosuppressants, and biologics are often prescribed to manage UC symptoms and induce remission.
  • Lifestyle Changes: Adopting a healthy diet, managing stress, and avoiding trigger foods can help alleviate symptoms.
  • Surgery: In severe cases or when medication fails to control symptoms, surgical removal of the colon (colectomy) may be necessary.

Complications of Ulcerative Colitis:

If left untreated or poorly managed, Ulcerative Colitis can lead to complications, such as:

  • Severe Bleeding: Chronic inflammation and ulcers can cause severe rectal bleeding.
  • Perforation: In rare cases, inflammation can weaken the colon wall, leading to perforation (a hole) in the bowel.
  • Colon Cancer: Long-standing UC increases the risk of developing colon cancer.

Prevention Techniques:

While the exact prevention of Ulcerative Colitis is not yet possible, certain lifestyle choices may help reduce the risk or manage symptoms:

  • Eating a Healthy Diet: Consuming a balanced diet rich in fruits, vegetables, whole grains, and lean proteins can promote gut health.
  • Managing Stress: Stress reduction techniques such as exercise, meditation, and therapy can help manage UC symptoms.
  • Avoiding Smoking: Not smoking or quitting smoking can significantly reduce the risk of developing UC.

Ulcerative Colitis (UC) is a chronic inflammatory bowel disease that affects millions of people worldwide. Managing this condition requires specialized care and comprehensive treatment. Marengo Asia Hospitals, spanning across India, has gained recognition for its patient-centric approach and expertise in handling complex medical cases. In this article, we will explore how Marengo Asia Hospitals addresses the unique challenges presented by Ulcerative Colitis, offering a ray of hope to patients and their families.

Multidisciplinary Team of Specialists:

Marengo Asia Hospitals boasts a skilled team of healthcare professionals specializing in gastroenterology and inflammatory bowel diseases. The hospitals’ multidisciplinary approach brings together gastroenterologists, colorectal surgeons, nutritionists, and other allied healthcare experts to create personalized treatment plans for each patient with UC. This collaborative effort ensures a comprehensive and holistic approach to care, addressing both the medical and psychosocial aspects of the disease.

Advanced Diagnostic Facilities:

Early and accurate diagnosis is crucial in managing Ulcerative Colitis effectively. Marengo Asia Hospitals is equipped with state-of-the-art diagnostic facilities, including advanced endoscopy, imaging, and laboratory services. These facilities enable prompt identification and monitoring of the disease, allowing physicians to tailor treatment strategies based on the severity and extent of inflammation.

Tailored Treatment Plans:

Every patient’s journey with Ulcerative Colitis is unique, necessitating personalized treatment plans. Marengo Asia Hospitals recognizes this individuality and emphasizes tailored approaches to patient care. Their experts take into consideration factors such as disease severity, location, and associated complications to develop customized treatment strategies. Treatment options may include medication management, lifestyle modifications, nutritional support, and surgical interventions when necessary.

Medication Management:

Marengo Asia Hospitals maintains an up-to-date knowledge of the latest advancements in medical therapy for Ulcerative Colitis. Their specialists are well-versed in administering conventional drugs, such as aminosalicylates, corticosteroids, and immunomodulators. Additionally, they are well-versed in managing the newer class of biologic therapies that target specific molecules involved in the inflammatory process. This expertise allows them to optimize medication regimens to control disease activity and minimize potential side effects.

Surgical Expertise:

In some cases, surgical intervention may be necessary to improve the quality of life for individuals with Ulcerative Colitis. Marengo Asia Hospitals comprises skilled colorectal surgeons who specialize in procedures like colectomy, ileal pouch-anal anastomosis (IPAA), and restorative proctocolectomy. Their proficiency in minimally invasive techniques, such as laparoscopy, ensures faster recovery, reduced postoperative complications, and improved outcomes.

Patient Education and Support:

Living with Ulcerative Colitis can be challenging for patients and their families. Marengo Asia Hospitals recognizes the importance of patient education and support throughout the treatment process. They offer educational resources, support groups, and counseling services to help patients better understand their condition, manage their symptoms, and cope with the emotional aspects of the disease. This comprehensive support system empowers patients to actively participate in their own care, leading to improved treatment outcomes.

Ulcerative Colitis requires specialized care that addresses both the medical and emotional needs of patients. Marengo Asia Hospitals, spread across India, has established itself as a leading provider of comprehensive care for individuals with this chronic inflammatory bowel disease. By employing a multidisciplinary team, utilizing advanced diagnostic facilities, offering tailored treatment plans, managing medications effectively, providing surgical expertise, and emphasizing patient education and support, they ensure that individuals with Ulcerative Colitis receive the highest quality of care. Marengo Asia Hospitals stands as a beacon of hope for patients, assisting them in their journey towards improved health and a better quality of life.


Contact Us

Marengo CIMS Hospital
Off Science City Road, Sola, Ahmedabad – 380060
Gujarat, INDIA

24×7 Helpline +91 70 69 00 00 00
Phone: 079 4805 1200 or 1008
+91 79 2771 2771 or 72
Fax: +91 79 2771 2770
Mobile: +91 98250 66664 or +91 98250 66668
Ambulance: +91 98244 50000
Email: info@cims.org