– Autologous Bone Marrow Transplant

– Allogeneic Bone Marrow Transplant

– Umbilical Cord Blood Transplant

– Haploidentical Donor Transplant

– Reduced Intensity Transplant

– Syngeneic Transplantation

When facing serious health conditions like blood cancers (leukemia, lymphoma, multiple myeloma) or certain blood disorders, doctors may recommend a bone marrow transplant as a part of the treatment. One of the most advanced and widely used types of transplants is called an Autologous Bone Marrow Transplant (ABMT).

At Marengo Asia CIMS Hospital, Ahmedabad, our expert team specializes in safe and effective autologous bone marrow transplants, helping patients recover with world-class care.

What is an Autologous Bone Marrow Transplant?

In simple words, this is a procedure where a patient’s own healthy bone marrow cells are collected, stored, and then returned to the body after high-dose chemotherapy or radiation therapy.

Since the patient’s own cells are used, the risk of rejection or complications is much lower than in transplants from a donor.

Why is it Needed?

Doctors recommend an autologous transplant for patients with:
✔ Blood cancers like leukemia, lymphoma, or multiple myeloma
✔ Certain autoimmune diseases
✔ Severe blood disorders

Chemotherapy or radiation can damage the bone marrow, which is responsible for producing healthy blood cells. This transplant restores the bone marrow and helps the body recover faster.

How is the Procedure Done?

Step 1: Collecting Healthy Stem Cells

Before chemotherapy, doctors collect healthy stem cells from the patient’s bone marrow or blood using a special process called apheresis. These cells are then carefully frozen and stored.

Step 2: High-Dose Chemotherapy

The patient undergoes strong chemotherapy or radiation therapy to destroy the diseased cells in the body. This is an important step to eliminate cancer cells but also affects bone marrow.

Step 3: Transplanting the Stored Cells

Once chemotherapy is done, the stored healthy stem cells are reintroduced into the body through an IV drip, just like a blood transfusion.

Step 4: Recovery and Growth

The new cells start settling in the bone marrow and begin producing healthy blood cells. This process takes a few weeks, and the patient is closely monitored to prevent infections and complications.

Benefits of Autologous Bone Marrow Transplant

✔ Lower risk of rejection – Since the patient’s own cells are used
✔ Faster recovery compared to donor transplants
✔ Effective treatment for many blood-related conditions
✔ Reduces side effects of high-dose chemotherapy

Why Choose Marengo Asia CIMS Hospital for Bone Marrow Transplant?

✅ Expert Team – Experienced hematologists & transplant specialists
✅ Advanced Technology – State-of-the-art stem cell therapy & transplant facilities
✅ High Success Rates – Proven record of successful transplants
✅ Comprehensive Care – From diagnosis to post-transplant recovery

At Marengo Asia CIMS Hospital, Ahmedabad, we are committed to providing the best bone marrow transplant care with advanced technology, skilled doctors, and compassionate patient support.

If you or a loved one needs expert care for blood cancers or bone marrow disorders, consult our specialists today!

When patients suffer from severe blood cancers or genetic disorders, their bone marrow may not function properly. In such cases, a bone marrow transplant can be a life-saving treatment.

One of the most effective types of transplants is an Allogeneic Bone Marrow Transplant (Allo-BMT), where a healthy donor’s stem cells are used to replace damaged bone marrow.

At Marengo Asia CIMS Hospital, Ahmedabad, we specialize in safe and advanced allogeneic bone marrow transplants, ensuring the best possible outcomes for our patients.

What is an Allogeneic Bone Marrow Transplant?

In simple terms, this is a procedure where a patient receives healthy bone marrow cells from a matching donor. This donor could be:
✔ A family member (like a sibling or parent)
✔ An unrelated donor (found through donor registries)
✔ Umbilical cord blood (from newborns, stored in a blood bank)

Since the donor’s healthy cells replace the patient’s diseased or damaged bone marrow, the transplant helps restore normal blood production and strengthens the immune system.

Why is it Needed?

Doctors recommend an allogeneic transplant for patients with:
✔ Blood cancers (Leukemia, Lymphoma, Multiple Myeloma)
✔ Bone marrow failure disorders (Aplastic anemia, Myelodysplastic syndrome)
✔ Genetic blood diseases (Thalassemia, Sickle Cell Disease)
✔ Severe immune system disorders

Unlike autologous transplants, where the patient’s own cells are used, an allogeneic transplant is required when the patient’s bone marrow cannot be saved.

How is the Procedure Done?

Step 1: Finding a Suitable Donor

A donor is selected based on HLA matching (a genetic test to ensure compatibility). A close family member is often the best match, but unrelated donors can also be found.

Step 2: Preparing the Patient

Before the transplant, the patient undergoes strong chemotherapy or radiation to destroy diseased bone marrow and prepare the body for new stem cells.

Step 3: Transplanting Donor Stem Cells

The healthy donor stem cells are infused into the patient’s bloodstream through an IV drip, similar to a blood transfusion.

Step 4: Recovery and Growth

The new cells travel to the bone marrow, settle in, and start producing healthy blood cells. This process, called engraftment, takes a few weeks, and the patient is closely monitored for complications.

Benefits of Allogeneic Bone Marrow Transplant

✔ Effective for severe diseases that cannot be treated with chemotherapy alone
✔ Offers a fresh immune system to fight cancer and infections
✔ Higher chance of long-term remission in blood cancers
✔ Can correct genetic disorders by replacing faulty bone marrow

Possible Risks & How We Manage Them

Since the donor’s cells are foreign to the patient’s body, there is a risk of:
⚠ Graft-versus-host disease (GVHD) – The new immune cells may attack the patient’s body. Our doctors manage this with advanced immunosuppressive therapy.
⚠ Infections – The immune system is weak during recovery. We provide top-class infection control care.
⚠ Rejection of donor cells – Careful monitoring and medications help prevent this.

Why Choose Marengo Asia CIMS Hospital for Bone Marrow Transplant?

✅ World-Class Transplant Experts – Experienced hematologists & oncologists
✅ Advanced Stem Cell Lab – Cutting-edge technology for better outcomes
✅ Comprehensive Patient Care – From donor matching to post-transplant recovery
✅ Proven Track Record – High success rates in complex transplants

At Marengo Asia CIMS Hospital, Ahmedabad, we are committed to providing world-class bone marrow transplant care with advanced technology and expert medical teams.

If you or a loved one needs a bone marrow transplant, consult our specialists today!

When it comes to treating serious blood disorders, cancers, and immune system diseases, bone marrow transplants are a powerful option. One advanced method is the Umbilical Cord Blood Transplant (UCBT), which uses stem cells from the umbilical cord of a newborn baby to replace damaged bone marrow.

At Marengo Asia CIMS Hospital, Ahmedabad, we offer cutting-edge umbilical cord blood transplants, providing new hope for patients with life-threatening conditions.

What is an Umbilical Cord Blood Transplant?

During birth, the umbilical cord (which connects the baby to the mother) contains rich stem cells that can grow into healthy blood cells. These cells can be collected, stored, and later used for transplantation in patients who need bone marrow replacement.

Since cord blood stem cells are young and adaptable, they do not require a perfect donor match like other types of transplants. This makes them an excellent option when a well-matched donor is not available.

Who Needs an Umbilical Cord Blood Transplant?

Doctors recommend UCBT for patients with:
✔ Blood cancers (Leukemia, Lymphoma)
✔ Bone marrow failure syndromes (Aplastic anemia, Myelodysplastic syndrome)
✔ Genetic blood disorders (Thalassemia, Sickle Cell Disease)
✔ Immune system disorders (Severe Combined Immunodeficiency – SCID)

Since cord blood transplants do not require an exact match, they are especially helpful for patients who struggle to find a compatible donor.

How is the Procedure Done?

Step 1: Finding a Suitable Cord Blood Unit

Cord blood is collected at birth and stored in special cord blood banks. Doctors search for a matching unit in these banks.

Step 2: Preparing the Patient

Before the transplant, the patient undergoes strong chemotherapy or radiation to destroy diseased bone marrow and make space for the new stem cells.

Step 3: Infusing the Cord Blood Stem Cells

The stored cord blood stem cells are infused into the patient’s bloodstream through an IV drip. These cells then travel to the bone marrow and begin to grow.

Step 4: Recovery and Growth (Engraftment)

The new stem cells settle in the bone marrow and start producing healthy blood cells. This process, called engraftment, takes a few weeks, and the patient is carefully monitored for any complications.

Benefits of Umbilical Cord Blood Transplant

✔ Easier to match – Less risk of rejection compared to traditional donor transplants
✔ Lower risk of Graft-versus-Host Disease (GVHD) – The new immune cells are less likely to attack the patient’s body
✔ Quick availability – Stored cord blood units can be used immediately when needed
✔ Can be used for patients of all ages – Especially useful when a matched donor is not available

Possible Risks & How We Manage Them

⚠ Slower engraftment – Since cord blood contains fewer stem cells, recovery may take longer. Our team uses advanced supportive care to help patients during this period.
⚠ Risk of infections – The immune system is weak after the transplant, so we provide highly specialized infection control care.
⚠ Graft failure – In some cases, the new cells may not grow properly. Our expert team carefully monitors and manages such risks.

Why Choose Marengo Asia CIMS Hospital for Umbilical Cord Blood Transplant?

✅ Expert Transplant Team – Skilled hematologists & transplant specialists
✅ Advanced Cord Blood Bank Access – Quick availability of high-quality cord blood units
✅ Cutting-Edge Technology – State-of-the-art transplant and stem cell facilities
✅ Comprehensive Post-Transplant Care – Specialized recovery and monitoring for best outcomes

At Marengo Asia CIMS Hospital, Ahmedabad, we are committed to providing world-class umbilical cord blood transplants with the latest technology and expert care.

If you or a loved one needs a bone marrow transplant and are exploring cord blood options, consult our specialists today!

For patients suffering from blood cancers, bone marrow failure syndromes, or genetic disorders, a bone marrow transplant can be a life-saving treatment. However, finding a fully matched donor is often a challenge.

In such cases, a Haploidentical Donor Transplant (Haplo-BMT) is a groundbreaking solution, allowing patients to receive a transplant from a partially matched family member.

At Marengo Asia CIMS Hospital, Ahmedabad, we offer advanced haploidentical transplants, giving new hope to patients who may not find a perfect donor match.

What is a Haploidentical Donor Transplant?

A haploidentical transplant is a type of allogeneic bone marrow transplant, where the donor is a half-matched (haploidentical) relative, usually:
✔ A parent
✔ A sibling
✔ A child

Unlike traditional donor transplants, which require a nearly perfect HLA match, haploidentical transplants allow a close but partial match, making transplants possible for more patients, faster.

Who Needs a Haploidentical Transplant?

Doctors recommend Haplo-BMT for patients with:
✔ Blood cancers (Leukemia, Lymphoma, Multiple Myeloma)
✔ Bone marrow failure syndromes (Aplastic anemia, Myelodysplastic syndrome)
✔ Genetic blood disorders (Sickle Cell Disease, Thalassemia)
✔ Immune system disorders

For patients who do not have a perfectly matched sibling or unrelated donor, haploidentical transplantation offers a life-saving alternative.

How is the Procedure Done?

Step 1: Finding a Suitable Family Donor

A parent, sibling, or child undergoes HLA testing to confirm they are at least a 50% match to the patient.

Step 2: Preparing the Patient

The patient undergoes high-dose chemotherapy or radiation therapy to destroy diseased bone marrow and prepare for the new stem cells.

Step 3: Collecting & Processing the Donor’s Stem Cells

The donor’s bone marrow or blood stem cells are collected and specially processed to reduce the risk of complications.

Step 4: Transplanting the Stem Cells

The donor’s healthy stem cells are infused into the patient’s bloodstream, where they migrate to the bone marrow and begin growing.

Step 5: Recovery & Engraftment

Over 2 to 4 weeks, the transplanted stem cells settle in the bone marrow and start producing healthy blood cells. During this time, patients are closely monitored for complications.

Benefits of Haploidentical Transplant

✔ More patients can receive transplants – No need to wait for a perfect match
✔ Faster donor availability – A family member can donate quickly
✔ High success rates with modern techniques
✔ Effective in treating high-risk diseases

Possible Risks & How We Manage Them

⚠ Graft-versus-host disease (GVHD) – Since the donor’s immune cells are not a perfect match, they may attack the patient’s body. Our team uses advanced immunosuppressive therapy to prevent and control GVHD.
⚠ Risk of infections – The immune system takes time to rebuild, so we provide world-class infection prevention and supportive care.
⚠ Graft failure – Our specialized team carefully monitors patients to ensure successful engraftment.

Why Choose Marengo Asia CIMS Hospital for Haploidentical Transplant?

✅ Expert Transplant Specialists – Experienced doctors in haploidentical transplants
✅ Advanced Stem Cell Therapy – Cutting-edge technology for improved outcomes
✅ Comprehensive Post-Transplant Care – Ensuring smooth recovery & long-term success
✅ World-Class Facilities – Equipped for safe & effective bone marrow transplants

At Marengo Asia CIMS Hospital, Ahmedabad, we are dedicated to providing the best and most advanced bone marrow transplant options to help patients fight life-threatening diseases.

If you or a loved one needs a bone marrow transplant and cannot find a fully matched donor, a haploidentical transplant could be the solution.

For patients suffering from blood cancers, bone marrow failure, or genetic disorders, a bone marrow transplant can be a life-saving procedure. However, not all patients can tolerate the high-dose chemotherapy or radiation required in a standard transplant.

This is where a Reduced Intensity Transplant (RIT)—also called a mini-transplant—comes in. It is a less aggressive but still highly effective approach, especially for older patients or those with other health issues.

At Marengo Asia CIMS Hospital, Ahmedabad, we offer advanced reduced-intensity transplants, giving more patients a chance at recovery with fewer risks.

What is a Reduced Intensity Transplant?

A Reduced Intensity Transplant (RIT) is a type of allogeneic bone marrow transplant, but instead of using very high doses of chemotherapy or radiation, doctors use a lower, more tolerable dose. This approach allows the body to accept healthy donor stem cells while reducing severe side effects.

Since this is a donor-based transplant, the new immune cells not only replace the diseased bone marrow but also help fight cancer cells—a process called the graft-versus-tumor effect.

Who Needs a Reduced Intensity Transplant?

Doctors recommend RIT for:
✔ Older patients (above 50-60 years) who cannot tolerate strong chemotherapy
✔ Patients with other serious health conditions (heart, liver, or kidney disease)
✔ Blood cancers (Leukemia, Lymphoma, Myelodysplastic syndrome)
✔ Bone marrow failure disorders (Aplastic anemia)
✔ Genetic diseases (Thalassemia, Sickle Cell Disease)

By using a gentler approach, RIT makes transplants possible for patients who otherwise wouldn’t qualify for a standard transplant.

How is the Procedure Done?

Step 1: Finding a Suitable Donor

The patient receives stem cells from a matched donor, which could be:
✔ A fully matched sibling or unrelated donor
✔ A haploidentical (half-matched) family member
✔ Umbilical cord blood stem cells

Step 2: Preparing the Patient (Conditioning)

Instead of very high-dose chemotherapy or radiation, the patient receives:
✔ Lower doses of chemotherapy and/or radiation
✔ Immunosuppressive therapy (to help the body accept donor cells)

Step 3: Transplanting the Donor Stem Cells

The donor’s healthy stem cells are infused into the patient’s bloodstream, where they travel to the bone marrow and begin growing.

Step 4: Recovery & Engraftment

Over the next few weeks, the new stem cells settle in the bone marrow and start producing healthy blood cells.

Benefits of a Reduced Intensity Transplant

✔ Less toxic, fewer side effects – Makes transplants possible for older or weaker patients
✔ Gentler on organs – Reduces risks for those with other health conditions
✔ Graft-versus-Tumor effect – The donor’s immune cells help fight cancer
✔ High success rates – Studies show good long-term outcomes in the right patients

Possible Risks & How We Manage Them

⚠ Graft-versus-host disease (GVHD) – Since the donor’s cells attack the patient’s body, we use special medications to control it.
⚠ Weaker immune system – The lower chemotherapy dose means some cancer cells may remain, so close monitoring is essential.
⚠ Infections – The immune system takes time to recover, so we provide expert infection control care.

Why Choose Marengo Asia CIMS Hospital for Reduced Intensity Transplant?

✅ Experienced Transplant Experts – Specialists in RIT for complex cases
✅ Advanced Stem Cell Therapy – Cutting-edge transplant techniques
✅ Comprehensive Patient Care – From donor matching to long-term recovery
✅ World-Class Facilities – Equipped for safe and successful transplants

At Marengo Asia CIMS Hospital, Ahmedabad, we are dedicated to making bone marrow transplants safer and more accessible with reduced-intensity conditioning.

If you or a loved one needs a bone marrow transplant but cannot tolerate high-dose chemotherapy, a Reduced Intensity Transplant could be the right solution.

A bone marrow transplant is a life-saving procedure for patients suffering from blood cancers, genetic disorders, and bone marrow failure syndromes. While most transplants require a partially or fully matched donor, the rarest and most ideal type of transplant is a Syngeneic Transplant.

At Marengo Asia CIMS Hospital, Ahmedabad, we specialize in Syngeneic Transplantation, ensuring the best possible outcomes for patients with the most compatible donor—an identical twin.

What is Syngeneic Transplantation?

A Syngeneic Transplant is a bone marrow or stem cell transplant between identical twins. Since identical twins have the exact same genetic makeup, the donor’s stem cells are a perfect match for the patient.

This type of transplant has the lowest risk of rejection and no risk of graft-versus-host disease (GVHD), making it the safest and most successful type of bone marrow transplant.

Who Needs a Syngeneic Transplant?

Doctors recommend Syngeneic Transplantation for patients with:
✔ Blood cancers (Leukemia, Lymphoma, Multiple Myeloma)
✔ Bone marrow failure syndromes (Aplastic anemia, Myelodysplastic syndrome)
✔ Genetic blood disorders (Thalassemia, Sickle Cell Disease)
✔ Certain immune system disorders

Since identical twins share the same DNA, a syngeneic transplant offers the best chance for a successful recovery.

How is the Procedure Done?

Step 1: Identifying an Identical Twin Donor

Since this transplant is only possible between identical twins, genetic testing confirms the match.

Step 2: Preparing the Patient (Conditioning Therapy)

The patient receives chemotherapy and/or radiation therapy to destroy diseased bone marrow and make space for new stem cells.

Step 3: Collecting & Transplanting Stem Cells

✔ Bone marrow or peripheral blood stem cells are collected from the healthy twin donor.
✔ The donor’s healthy stem cells are infused into the patient’s bloodstream, where they travel to the bone marrow and start growing.

Step 4: Recovery & Engraftment

Within 2 to 4 weeks, the new stem cells settle in the bone marrow and start producing healthy blood cells. Since the donor and patient are genetically identical, the risk of complications is extremely low.

Benefits of Syngeneic Transplantation

✔ No risk of rejection – The donor’s cells are a perfect match
✔ No graft-versus-host disease (GVHD) – The new immune cells won’t attack the patient’s body
✔ High success rates – Faster recovery with fewer complications
✔ Effective treatment for blood disorders – Can cure leukemia, aplastic anemia, and genetic diseases

Possible Risks & How We Manage Them

⚠ Relapse of cancer – Since there’s no graft-versus-tumor effect (unlike in allogeneic transplants), cancer cells might return. Our specialists monitor patients closely and may recommend additional treatments if needed.
⚠ Infections – Patients still need time to rebuild their immune system, so we provide top-class infection prevention care.

Why Choose Marengo Asia CIMS Hospital for Syngeneic Transplantation?

✅ Expert Transplant Specialists – Skilled in advanced stem cell therapies
✅ State-of-the-Art Stem Cell Facilities – Ensuring the safest transplant procedures
✅ Comprehensive Post-Transplant Care – Focused on long-term health & recovery
✅ World-Class Hospital Infrastructure – Designed for high-quality patient care

At Marengo Asia CIMS Hospital, Ahmedabad, we provide the best possible care for patients undergoing Syngeneic Transplantation, giving them a new chance at a healthy life.

If you or a loved one is an identical twin and in need of a bone marrow transplant, a Syngeneic Transplant could be the best option.