ITP (Immune Thrombocytopenia)

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Immune Thrombocytopenia (ITP) is a challenging blood disorder that affects individuals in India. This article aims to provide detailed insights into ITP, including its signs and symptoms, classification, causes, risk factors, types, diagnostic tests, treatment options, complications, prevention techniques, and examples of public figures in India who have been diagnosed with this condition. By increasing awareness and understanding, we hope to support those affected and their families.

Signs and Symptoms:

The signs and symptoms of ITP may include:

1. Easy or excessive bruising

2. Prolonged or excessive bleeding from minor cuts or injuries

3. Petechiae (small red or purple spots on the skin)

4. Excessive nosebleeds or bleeding gums

5. Blood in urine or stools

6. Fatigue and weakness

7. Enlarged spleen in some cases

What is ITP (Immune Thrombocytopenia)?

ITP, also known as immune thrombocytopenic purpura, is an autoimmune disorder characterized by low platelet count. Platelets are essential for blood clotting, and their deficiency can lead to increased bleeding and bruising. In ITP, the immune system mistakenly attacks and destroys platelets, resulting in a decreased number of functional platelets in the bloodstream.

How is ITP (Immune Thrombocytopenia) Classified?

ITP can be classified based on the duration of the condition:

1. Acute ITP: Generally seen in children, lasting for less than six months.

2. Chronic ITP: Lasting for six months or longer, often diagnosed in adults.

Causes and Triggers:

The exact cause of ITP is unknown. However, it is believed to be an autoimmune disorder, where the immune system mistakenly targets and destroys platelets. Certain triggers may contribute to the development or exacerbation of ITP, including viral infections, medications, and other underlying health conditions.

Risk Factors with Examples:

While ITP can occur in individuals of any age, certain risk factors may increase the likelihood of developing the condition, including:

1. Age: Children and young adults are more commonly affected by acute ITP, whereas chronic ITP is more prevalent in adults.

2. Gender: ITP is more common in females compared to males.

3. Viral infections: Some viral infections, such as Epstein-Barr virus (EBV), hepatitis C, or HIV, have been associated with the development of ITP.

4. Medications: Certain medications, including antibiotics, anticonvulsants, and nonsteroidal anti-inflammatory drugs (NSAIDs), may trigger ITP in some individuals.

5. Other autoimmune disorders: Individuals with other autoimmune disorders, such as lupus or rheumatoid arthritis, have an increased risk of developing ITP.

Types of ITP (Immune Thrombocytopenia):

1. Primary (Idiopathic) ITP: The most common type, where the cause is unknown.

2. Secondary ITP: ITP that occurs as a result of another underlying condition, such as an autoimmune disorder or certain infections.

Diagnostic Tests and Treatments:

Diagnosing and treating ITP involves several approaches:

1. Complete blood count (CBC): This test measures the number of platelets, red blood cells, and white blood cells in the bloodstream. A low platelet count (thrombocytopenia) is a characteristic finding in ITP.

2. Blood smear: A blood sample is examined under a microscope to evaluate the appearance and function of platelets.

3. Bone marrow biopsy: In certain cases, a small sample of bone marrow may be collected and examined to assess platelet production and rule out other underlying conditions.

4. Treatment options: The treatment for ITP depends on the severity of symptoms and platelet count. Options may include medications to suppress the immune system, such as corticosteroids or intravenous immunoglobulin (IVIG). In severe cases, procedures like splenectomy (spleen removal) may be considered to improve platelet count.

Complications of ITP and Prevention Techniques:

Complications of ITP may include excessive bleeding, particularly in critical areas like the brain or gastrointestinal tract. While there are no specific preventive measures for ITP, individuals can take general precautions to minimize the risk of bleeding, such as avoiding activities that may cause injury, practicing good oral hygiene to prevent gum bleeding, and promptly reporting any unusual bleeding or bruising to healthcare providers

ITP (Immune Thrombocytopenia) is a complex blood disorder that requires specialized care and management. Marengo Asia Hospitals, known for its excellence in healthcare, plays a vital role in handling patients with ITP across India. This article explores the comprehensive approach taken by Marengo Asia Hospitals in diagnosing, treating, and supporting patients with ITP, emphasizing their expertise in hematology and autoimmune disorders.

Specialized Hematology Department:

Marengo Asia Hospitals houses a team of highly skilled hematologists who specialize in managing blood disorders, including ITP. These experts have extensive experience in diagnosing and treating ITP, ensuring that patients receive individualized and effective care.

Accurate Diagnosis:

Accurate diagnosis is crucial for effective management of ITP. Marengo Asia Hospitals employs a comprehensive diagnostic process, which may include:

1. Complete blood count (CBC): This test measures the number of platelets, red blood cells, and white blood cells in the bloodstream. A low platelet count (thrombocytopenia) is a characteristic finding in ITP.

2. Blood smear: A blood sample is examined under a microscope to evaluate the appearance and function of platelets and rule out other potential causes of thrombocytopenia.

3. Bone marrow biopsy: In some cases, a small sample of bone marrow may be collected and examined to assess platelet production and rule out other underlying conditions.

Personalized Treatment Plans:

Once diagnosed, the Marengo Asia  Hospitals develops personalized treatment plans tailored to each patient’s specific needs. Treatment options for ITP may include:

1. Medications to boost platelet count: Corticosteroids, intravenous immunoglobulin (IVIG), and immunosuppressive drugs may be prescribed to stimulate platelet production and prevent platelet destruction by the immune system.

2. Splenectomy: In severe cases or when other treatments fail, surgical removal of the spleen may be considered as a means to improve platelet counts.

3. Supportive care: Marengo Asia Hospitals provides comprehensive supportive care to manage symptoms and minimize the risk of bleeding. This may include education on self-care, wound management, and guidelines for activity restrictions.

Regular Monitoring and Follow-up:

Patients with ITP require regular monitoring to assess treatment response and adjust treatment plans as needed. Hematologists at Marengo Asia Hospitals closely monitor platelet counts and overall health, ensuring that patients receive appropriate care and support throughout their treatment journey.

Collaboration with Multidisciplinary Teams:

Marengo Asia Hospitals recognizes that managing ITP requires a multidisciplinary approach. Hematologists collaborate closely with other medical disciplines, such as immunologists, pediatricians, and transfusion medicine specialists, to provide holistic care. This collaboration ensures that patients receive comprehensive and coordinated management, addressing all aspects of their condition.

Patient Education and Support:

The Marengo Asia Hospitals places great emphasis on patient education and support. Patients and their families are provided with comprehensive information about ITP, including its causes, treatment options, potential side effects of medications, and self-care strategies. The network also offers counseling services, support groups, and educational resources to empower patients in managing their condition and promoting their overall well-being.

Research and Advancements:

As a leading healthcare institution, Marengo Asia Hospitals actively participates in research and clinical trials to advance the understanding and treatment of ITP. By staying at the forefront of medical advancements, the network strives to offer the latest and most effective treatment options to patients.

Marengo Asia Hospitals across India is committed to providing comprehensive care for patients with ITP. With its specialized hematology department, accurate diagnosis, personalized treatment plans, regular monitoring, collaboration with multidisciplinary teams, patient education, and involvement in research, the network ensures that individuals affected by ITP receive the highest quality of care. Through their expertise and dedication, the Marengo Asia  Hospitals plays a crucial role in improving the lives of patients with ITP, offering hope, support, and effective management strategies.


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